T2 Relaxometry Secrets in Epilepsy Protocol

Hippocampal structural damage is equivocally depicted by spectroscopy. For diagnostic and pre-operative evaluation, hippocampal volumetry and T2-relaxometry provide maximal accuracy. Amygdala quantifications are irrelevant in the pre-operative evaluation but may be useful for diagnostic purposes. Of the three qMRI modalities tested, T2-relaxometry provided the best balance between diagnosis accuracy and time-efficiency to lateralize a sclerotic lesion on the majority of the patients. The salient points to rememberare:
- independent of magnetic strength, age, sex or side
- can be done not only in hippocampus but also in anterior temporal lobe, parietooccipiatal lobe, amgdela etc.
- complete symmetry exists between both sides (< 7 ms)
- normally should not exceed 90 to 97 ms
- if volume calculations and T2 values do not match believe the T2 values
- epileptogenic focus is the key to treatment

Submitted by Dr MGK Murthy (Elbit Medical Diagnostics)

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