Tarlov's cysts are located in the perineural space, between the endo-and perineurium at the junction of the posterior nerve root and its ganglion. These lesions either surrounded the entire nerve root or invaded it and became surrounded by compressed nerve fibers. Regardless of the nomenclature or classification system, the defining feature of Tarlov's perineural cyst is the presence of spinal nerve root fibers within the cyst wall or within the cyst cavity itself.The authors of one study found that patients with Tarlov cysts greater than 1.5 cm and with associated radicular pain or bowel/bladder dysfunction benefited most from surgery.
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