Monday, July 28, 2008

Giant Sigmoid Diverticulum



Giant sigmoid diverticulum is unusual, with only 103 cases previously reported in the world literature.These lesions probably arise as pseudodiverticula of the sigmoid colon with herniation of the mucosa through the muscle wall. The flap-valve mechanism with fibromuscular hyperplasia at the diverticular orifice seen by the pathologist confirms how this giant colonic diverticulum probably developed.All patients with giant sigmoid diverticula are generally elderly, with an age range of 40 to 90 years. The 19% complication rate associated with giant sigmoid diverticulum is relatively high.They are best treated by resection of the diverticulum, in continuity with the involved sigmoid, and primary anastomosis.

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Sunday, July 6, 2008

Neurocysticercosis



Cysticercosis remain a global public health problem in both the developing and developed countries. CT scan and MRI have been useful in the study of the evolution of the cysticercus within the brain parenchyma. MRI is more useful than CT scan in detecting intraventricular and subarachnoidal cysts, as well as the accompanying signs of cyst degeneration and pericystic inflammatory reaction. However, CT scan is preferred for detection of parenchymal calcifications.
Once the oncosphere has passed into the parenchyma, it grows and evolves through vesicular, colloidal, nodular-granular, and calcified phases. The racemose form constitutes a hydropic change that leads to large or even giant vesicles usually devoid of a scolex. Carpio proposed an improved and widely accepted classification system based on the viability and location of the parasite in the host CNS. Active, when the parasite is alive. Transitional, if it is in the degenerative phase. Inactive, if evidence of its death is apparent. Because of the variable clinical course of the disease, treatment must be individualized for each patient. It constitutes antiepileptic and antihelmintic therapy.

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SCFE - Slipped Capital femoral epiphysis


SCFE is one of the most common of the major disorders of the hip in adolescence. It affects boys somewhat more than girls. The usual age is about ten to sixteen years old. It will usually involve one side, but may occasionally be bilateral. SCFE is caused by multiple factors including local trauma, obesity overcoming the physeal plate, inflammatory factors, and possible endocrine abnormalities. Imaging will generally show the posteromedial slip. SCFE can be broken down into two categories: stable and unstable. A stable slip is defined as one where the child can still bear weight on the affected extremity. A slip is considered unstable if the child cannot bear weight on that extremity. Pain indicates that the physis has split. Treatment of a SCFE usually consists of in situ pinning using a cannulated screw introduced over a guide wire.

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Pulmonary Hydatid Cyst



Pulmonary hydatid is caused by larval stage of parasite Echinococcus granulosus. Although surgery still remains the definitive therapy, various workers have tried albendazole and sterilization of cysts with varying result.
Commonest site of cyst is in both lower lobes. X-ray signs include spherical cyst, crescent sign, water lily sign, double arch, pneumonia, hydropneumothorax and blunting of CP angle. In contrast to liver cysts in which calcification occurs in
20 to 30%, calcification of pulmonary hydatid cysts is rare (.07%).

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Ameloblastoma



Ameloblastoma is a rare, benign tumor of odontogenic epithelium (ameloblasts, or outside portion, of the teeth during development) much more commonly appearing in the mandible than the maxilla. Symptoms include painless swelling, facial deformity if severe enough, pain if the swelling impinges on other structures, loose teeth, ulcers, and periodontal (gum) disease. Lesions will occur in the mandible and maxilla,although 75% occur in the ascending ramus area and will result in extensive and grotesque deformitites of the mandible and maxilla. Radiographically, it appears as a lucency in the bone of varying size and features--sometimes it is a single, well-demarcated lesion whereas it often demonstrates as a multiloculated "soap bubble" appearance. Resorption of roots of involved teeth can be seen in some cases, but is not unique to ameloblastoma. Ameloblastomas are relatively resistant to chemotherapy or radiation therapy, thus, surgery is the most common treatment of this tumor.

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Cerebral Angioma



Cavernous angiomas belong to a group of intracranial vascular malformations that are developmental malformations of the vascular bed. These congenital abnormal vascular connections frequently enlarge over time. The lesions can occur on a familial basis. Patients may be asymptomatic, although they often present with headaches, seizures, or small parenchymal hemorrhages.
The sensitivity of MRI to flowing blood and blood products of varying ages, as well as the greater contrast resolution of MRIs, greatly increases the specificity of MRI compared with that of CT. Combining multiple MRI sequences has largely eliminated misdiagnosis of cavernous angiomas, because they have relatively specific signal characteristics. Additionally, gradient-echo imaging, with its increased sensitivity to susceptibility artifact, is useful in the detection of smaller and concomitant lesions, which may not be detected with traditional sequences.
Most cavernous malformations do not produce significant symptoms in patients, and most can simply be followed up over time. For patients in whom lesions cause significant neurologic morbidity, treatment options are available. These options differ depending on the location, size, and amount of the associated hemorrhage. Surgical resection is an option, but depending on the location of the lesion and the patient's existing comorbidities, surgical resection is not the best option in some cases. Stereotactic radiosurgery is an important option in AVMs and hemorrhagic cavernous malformations. The procedure is relatively contraindicated in patients with concomitant venous angiomas because of the high incidence of posttreatment morbidity.

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ABC - Aneurysmal Bone Cyst


An aneurysmal bone cyst is an expansile osteolytic lesion with a thin wall, containing blood-filled cystic cavities. The term aneurysmal is derived from its radiographic appearance. The clinical manifestation depends on the specific site of involvement. A common presentation includes pain of relatively acute onset that rapidly increases in severity over 6-12 weeks.The accuracy of radiography is high, especially with lesions in the appendicular skeleton. Cross-sectional imaging may be useful in defining the extent of spinal, thoracic cage, and pelvic bone involvement. Cross-sectional imaging may not increase the specificity to a large extent.
Differential includes brown tumors in hyperparathyroidism, expansile metastasis from renal cell carcinoma and thyroid carcinoma, hemophilic pseudotumor with hemorrhage,
infestation of bone by a hydatid cyst and telangiectatic osteosarcoma

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